Assuming American? William Faulkner and Sinclair Lewis (Nobel Prize each). Steinbeck and Hemingway also got it, but their greatness tends to be debated. Joseph Heller? I also like Woody Allen.
Ernest Hemingway, F. Scott Fitgerald, John Steinbeck, Joyce Carol Oates, Norman Mailer, Gore Vidal, Eudora Whelty, Harper Lee, Truman Capote, Kurt Vonnegut.