The majority of Little House On The Prarie was filmed on Big Sky Ranch in Simi Valley California. Some parts were also filmed in northern California, specifically, Tuolumne county.
It was filmed at Big Sky Ranch located in Simi Valley, California. The area had some rugged terrain which was dissimilar in appearance from prairie land in Minnesota.
you would think it was made in the south but it was actually made in the deserts of California. There's not just one particular place though, it was filmed in a few different cities.