Well if you just mean a system with a slightly dirty system then all you really need to do is run a few tanks of high quality octane fuels. The higher quality fuel will help to remove deposits left from lower quality gas. Fuel system cleaners can be added also to clean injectors and other components.
We can use solvents to clean,that can be added to gas tank. After solution to the tank,run the engine. The solvent will clean injectors,fuel lines,cylinders and fuel pump.