Answer by
tk7544 (149)
I would say the best medication for Acid Reflux would be a PPI(Proton Pump Inhibitor). If you have tried and failed most of the OTC medications, you may have severe reflux. I would suggest using the Nexium or Aciphex. These are very popular drugs in that therapy class. They assist with healing your esophegus as well as treating GERD.