Should I be concerned about an elevated ca-125?

Answer by  Kris58 (36)

Possibly. When having this test come back with elevated ca-125, further testing is usually needed. This can be anything from double negative result to a malignancy.

Answer by  serena (79)

Yes you need to be concerned about it. It is usually there due to ovarian malignancy or gastrointerstinal malignancy. Ovarian malignancy is like germcell tumors or stromal tumors. It can cause markedly elevated ca-125 level. Screening test eg Sonogram should be done to find out the underline cause. Once confirmed it has progonostic value.

Answer by  GaryMaine (6)

You don't have to be concerned but you have to do some other exams, as ca-125 is a tumor marker but its level can be elevated even in a lot of benign diseases, as endometriosis, and in pregnancy. Even as a tumor marker, ca-125 is consider not very specific nor very sensitive, so it's not realiable for diagnosis.