Answer by  
                                                                                          Darkephoenix (1789)
                                                            
                          
                          
                                                          A very mild soap and water solution is best for pearls.  Do not rub excessively on them, this will wear off the nacre on them.  Put them on a very soft cloth and allow to air dry.  NEVER allow them to be put in a sonic cleaner.  Make sure they are restrung periodically if you wear them often.