If your F150 has trouble starting and runs rough, you should first drain the oil and run an engine cleanser through the system. This will clean out any dirt.
Check the control head for most problems with overheating and engine troubles. Stalling out and running rough (bumpy between gears) is a problem with the transmission. Starting troubles would be oil pressure and the battery.
The first thing you should do is check the fuel filter, this should be somewhere along the fuel line, and could cause problems starting, engine stalling and running rough.