The process is the same as regular tile. But as your tile is smaller use a smaller notched trowel this will help keep the thinset from filling the joints and making a mess for when you have to grout. Also make sure your sheet is laying flat so all of sheet is making contact with thinset.
Depending on where your laying it floors, walls, showers, etc.. in most cases you will use a mastic trowel to spread your mastic glue. Then cut and install tile.