There is no silver bullet. You'll need to weed-and-feed regularly, following a year-round sequence of a good vendor's yard products. Remove particularly tough weeds directly and re-sod where needed.
The most natural way to remove weeds is by-hand. Pull up as much of the roots with the weed as possible. Each time the weeds re-sprout, there will be less.
go to the store and buy some weed remover and put it at the base of the roots on the weeds. after you kill them all they wont grow back make sure you get them all tho