Being a truck driver requires a commercial driver's license. Most commonly, you will enroll in a trade school or truck driving school in order to get this. You will need to have a clean driving record, as well.
To enter into the truck driving field I think you should talk to some truck drivers. They can answer how they entered into the field and the various demands of the job. You could also take a course on driving a truck and then apply to various trucking companies.