During the denaturation of enzymes, what happens to the shape and tertiary structure of the enzymes?

Answer by  Jenn09 (176)

During denaturation (usually due to changes in the ionic or temperature of the solution), the folded enzyme will lose it's shape. The components of the tertiary structure normally disassociate, thereby causing the enzyme to lose it's activity. Depending on the strength of the denaturation, the protein may be reduced as far as it's primary structure.

Answer by  billyhulai (17)

The tertiary structure, that is the arrangements of secondary structures such as coils or helixes, are destroyed during denature and the enzymes become inactive.

Answer by  Anonymous

the above is incorrect.