That depends. Housecalls detects malware and harmful data that could ruin your computer. If you have another antivirus or antimalware solution you prefer, you can get rid of it.
Trend Micro's House Call is a virus scanner product that keeps protects your computer from viruses. Your computer will not need it to run but it is important to use a virus scanner.
Trend micro is a form of anti-virus software, that may come as a trial on your computer, so long as you have a form of anti-virus you should delete it.