Answer by
soothsayer (500)
Prilosec or omeprazole is a proton pump inhibitor while Zantac or ranitidine is an H1 blocker. Both have proven to be effective in acid-peptic disease by decreasing the production of acid. Ranitidine is usually initiated as first-line therapy and if required[persisting symptoms],omeprazole is advised as this has a more stronger acid-supression effect.