Answer by  
                                                                                          MedStudent01 (1131)
                                                            
                          
                          
                                                          The theory is that the increased levels of estrogen in the body increase the production of cholesterol in your body.  This increase in cholesterol causes a reflex increase in bile and reduced gallbladder movement as well, setting a person up for gallstone formation.  The pain is caused by a stone blocking the gallbladder's duct.