Get down on your hands and knees and look around. Are their things that if chewed on would hurt your puppies? Are their things within reach that you don't want your puppies to get into or chew on? Make sure you have toys and a soft safe place for them to sleep, and newspaper until they are housebroken.
You should start puppy proofing the home. Make sure anything that you don't want them to chew is picked up. Take anything that is dangerous for your puppy and either block it off with a baby gate or put it where the puppy cannot reach it. Puppies will chew on anything, so give them dog toys they can chew.
Puppies need nearly constant supervision. Keep them in a small, enclosed area, gating off any place you can't be with them. Make sure they can't get to electric cords and other hazards. Crates are your friend; puppies are most comfortable in small places. To avoid accidents from rambunctious play, it's best if each puppy has its own crate.
Get an old wind-up alarm clock. Put it in the box or dog bed where they will be sleeping at night. The steady tick of the clock will remind them of their mother's heartbeat and help them to sleep.